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  2. Dexmedetomidine - Wikipedia

    en.wikipedia.org/wiki/Dexmedetomidine

    Dexmedetomidine, sold under the brand name Precedex among others, is a medication used for sedation. [4] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. [ 10 ] [ 11 ] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar disorder . [ 5 ]

  3. Drug titration - Wikipedia

    en.wikipedia.org/wiki/Drug_titration

    Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]

  4. List of investigational agitation drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    Aripiprazole (Abilify) – atypical antipsychotic (non-selective monoamine receptor modulator) [1]; Bupropion/dextromethorphan (AXS-05; Auvelity) – sigma σ 1 receptor agonist, serotonin reuptake inhibitor, norepinephrine and dopamine reuptake inhibitor, nicotinic acetylcholine receptor negative allosteric modulator, ionotropic glutamate NMDA receptor antagonist, other actions, and CYP2D6 ...

  5. Alpha-2 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-2_blocker

    They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives, like xylazine, medetomidine and dexmedetomidine. Alpha-2 blockers increase noradrenaline release.

  6. Medetomidine - Wikipedia

    en.wikipedia.org/wiki/Medetomidine

    Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.

  7. Detomidine - Wikipedia

    en.wikipedia.org/wiki/Detomidine

    Detomidine is a sedative with analgesic properties. [3] α 2-adrenergic receptor agonists produce dose-dependent sedative and analgesic effects, mediated by activation of α 2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters.

  8. Diet in diabetes - Wikipedia

    en.wikipedia.org/wiki/Diet_in_diabetes

    [1] [2] Both vegan and vegetarian diets have been shown to be beneficial for weight loss in comparison to the standard American diet. [1] [17] For type 2 diabetics, the focus of a vegetarian or vegan diet should be maintaining a level of caloric intake that results in fat loss, adequate protein consumption, adequate consumption of compounds ...

  9. Atipamezole - Wikipedia

    en.wikipedia.org/wiki/Atipamezole

    Atipamezole is a veterinary drug whose prime purpose is to reverse the effects of the sedative dexmedetomidine (as well as its racemic mixture, medetomidine). [note 1] [9] [10] It can also be used to reverse the related sedative xylazine. [11]