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History of aspirin. Aspirin (acetylsalicylic acid), an organic compound that does not occur in nature, was first synthesised in 1899. In 1897, scientists at the drug and dye firm Bayer began investigating acetylated organic compounds as possible new medicines, following the success of acetanilide ten years earlier.
[13]: 69–75 [20] By 1899, Bayer had named it "Aspirin" and was selling it around the world. [15] Aspirin's popularity grew over the first half of the 20th century, leading to competition between many brands and formulations. [21] The word Aspirin was Bayer's brand name; however, its rights to the trademark were lost or sold in many countries ...
Edward Stone was born in Princes Risborough, Buckinghamshire, England, in 1702. His parents were Edward Stone, a gentleman farmer, and his first wife Elizabeth Reynolds. His mother having died, his father took a second wife, Elizabeth Grubb, in 1707; the Grubb family was to play a major role in Stone's life. [1]
Felix Hoffmann (21 January 1868 – 8 February 1946) was a German chemist notable for re-synthesising diamorphine (independently from C.R. Alder Wright who synthesized it 23 years earlier), which was popularized under the Bayer trade name of "heroin". He is also credited with synthesizing aspirin, though whether he did this under his own ...
Doctors used to recommend taking a low-dose aspirin daily, but this has changed in recent years. ... tells Yahoo Life: “Where aspirin is used more commonly these days is as an antiplatelet agent ...
Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of reducing inflammation. This reduces leukocyte adhesion, which is an important step in immune response to infection. There is currently insufficient evidence to show that aspirin helps to fight infection. [18]
Raffaele Piria (Scilla 20 August 1814 – Turin 18 July 1865) was an Italian chemist from Scilla, who lived in Palmi. He converted the substance Salicin into a sugar and a second component, which on oxidation becomes salicylic acid, a major component of the analgesic drug Aspirin (acetylsalicylic acid). [1] Other reactions discovered by Piria ...
Medicinal plants. The bark of willow trees contains salicylic acid, the active metabolite of aspirin, and has been used for millennia to relieve pain and reduce fever. [1] Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical ...