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Diacetyl is reported at lower levels in e-cigarettes than in traditional cigarettes. [238] 2, 3-pentanedione is an α-diketone that is chemically and structurally similar to diacetyl. A 2016 report stated that it had become a popular replacement for diacetyl, although it had been shown to cause airway epithelial damage similar to diacetyl. [179]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
There is concern that flavored e-cigarettes could have a similar impact on youth. [14] The extent to which teens are using e-cigarettes may lead to addiction or substance dependence in youth, is unknown. [89] A 2017 review noted that "adolescents experience symptoms of dependence at lower levels of nicotine exposure than adults.
In analyzing 51 different flavored e-cigarettes, author of the study Joseph Allen and his team found at least one of three top toxins — diacetyl, acetoin and 2,3-pentanedione — in 47 of the e ...
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This is an accepted version of this page This is the latest accepted revision, reviewed on 6 February 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...
Scott Gottlieb's crusade against teen use of e-cigarettes is not likely to go away.