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Nerve tissue loss is associated with the more severe nerve injuries. 50-60% of sensory and motor neurons has been calculated from experiments after the use of nerve grafts Schwann cells form myelin, insulation to the nerve to allow better conduction along the axon, around the nerve fibers and secrete growth factors that play a major role in the ...
A skin biopsy for the measurement of epidermal nerve fiber density is an increasingly common technique for the diagnosis of small fiber peripheral neuropathy. [13] Physicians can biopsy the skin with a 3-mm circular punch tool and immediately fix the specimen in 2% paraformaldehyde lysine-periodate or Zamboni's fixative. [20]
This type of nerve damage may cause paralysis of the motor, sensory, and autonomic functions, and is mainly seen in crush injury. [2] If the force creating the nerve damage is removed in a timely fashion, the axon may regenerate, leading to recovery. Electrically, the nerve shows rapid and complete degeneration, with loss of voluntary motor units.
The white space represents a disruption of the nerve fibers, resulting in a loss of nerve supply to the muscle fibers. Denervation is any loss of nerve supply regardless of the cause. If the nerves lost to denervation are part of neural communication to an organ system or for a specific tissue function, alterations to or compromise of ...
A nerve decompression is a neurosurgical procedure to relieve chronic, direct pressure on a nerve to treat nerve entrapment, a pain syndrome characterized by severe chronic pain and muscle weakness. In this way a nerve decompression targets the underlying pathophysiology of the syndrome and is considered a first-line surgical treatment option ...
The advantage of this procedure is that the vestibular nerve is clearly visible and can be sectioned without harming the cochlear nerve fibers. [ 7 ] The general procedure begins by positioning the patient supine with the head turned to the side with surgical ear upright.
[6] [2] [14] The agent of choice is injected into or adjacent to a specific sensory nerve or into muscle fibers to dull neuronal pain signaling. [ 6 ] [ 2 ] As chemical denervation agents, phenol and alcohol are inexpensive, fast-acting, and can be readministered or boosted within months, while also possibly causing scarring or fibrosis.
The aim of decompression surgery is to open the affected area and nerve sheath, and to release pressure. This reduces compression on the nerve fibers, improves blood circulation and minimizes damage to distal nerve fibers. Several surgicala approaches are described to achieve decompression: Middle cranial fossa approach [2] Translabarynthine ...