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Midazolam is known to cause respiratory depression. In healthy humans, 0.15 mg/kg of midazolam may cause respiratory depression, which is postulated to be a central nervous system (CNS) effect. [48] When midazolam is administered in combination with fentanyl, the incidence of hypoxemia or apnea becomes more likely. [49]
"The Milkman Conspiracy" is a level in the 2005 video game Psychonauts. It is a world that takes place in the mind of Boyd Cooper, a paranoid security guard of an asylum, which the protagonist Raz explores. The area has unusual gravity, causing Raz to be pulled towards different roads when he is near and walking at unusual angles.
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
Midazolam is the most commonly prescribed for this use because of its strong sedative actions and fast recovery time, as well as its water solubility, which reduces pain upon injection. Diazepam and lorazepam are sometimes used. Lorazepam has particularly marked amnesic properties that may make it more effective when amnesia is the desired effect.
Amobarbital, one of the chemical compounds that can be used as a truth serum. Sedatives or hypnotics that alter higher cognitive function include ethanol, scopolamine, 3-quinuclidinyl benzilate, potent short or intermediate acting hypnotic benzodiazepines such as midazolam, flunitrazepam, and various short and ultra-short acting barbiturates, including sodium thiopental (commonly known by the ...
In a study in rats, cross-tolerance between the benzodiazepine drug chlordiazepoxide and bretazenil has been demonstrated. [11] In a primate study bretazenil was found to be able to replace the full agonist diazepam in diazepam dependent primates without precipitating withdrawal effects, demonstrating cross tolerance between bretazenil and benzodiazepine agonists, whereas other partial ...
A futuristic healing machine capable of piercing into one's memories is Maxime's only hope to save her dying girlfriend. Along with the help of her mother Samantha (Fiona Dourif), the only person she knows that can operate the machine, Max must traverse into the dark recesses of her lover's mind in order to locate the "essential memory" that could save her life, all the while being hunted by a ...
Using his Clairvoyance ability, Raz discovers Truman is being held at an abandoned Psychonaut research facility in an oceanic region known as the Rhombus of Ruin (a play on the Bermuda Triangle), built to study a large underwater deposit of Psilirium (a fictional element variant of Psitanium that can distort psychic powers and creates illusions ...