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Macropinocytosis is a clathrin-independent endocytic mechanism that can be activated in practically all animal cells, resulting in uptake. In most cell types, it does not occur continuously but rather is induced for a limited time in response to cell-surface receptor activation by specific cargoes, including growth factors , ligands of ...
The different types of endocytosis. Endocytosis is a cellular process in which substances are brought into the cell. The material to be internalized is surrounded by an area of cell membrane, which then buds off inside the cell to form a vesicle containing the ingested materials.
Here, both infectious forms of VACV, mature virion (MV) and enveloped virion (EV), induce their own macropinocytosis by binding to the cell surface and triggering an actin-mediated plasma membrane protrusion that eventually collapses back onto the plasma membrane sealing the attached virion inside a macropinosome, which then goes through a ...
Women with diabetes may get the strongest cardiovascular protection from GLP-1 agonists. Image credit: Kathryn Gamble for The Washington Post via Getty Images.
Tau can become phosphorylated, meaning that phosphate groups are added to it. This is normal, but in the case of Alzheimer’s, the phosphorylation is abnormal or excessive.
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Cosimo Commisso is a Canadian cell biologist and cancer researcher who has made significant advances in the field of cellular trafficking and cancer metabolism. [1] [2] [3] Among his most notable contributions are the discovery and study of how macropinocytosis supports tumor cell growth and survival by serving as an amino acid supply route in Ras-mutated cancers.
Meaning, Travis and the Chiefs are presumably in New Orleans practicing for the game and are on a pretty strict schedule that doesn’t involve jetting off to Los Angeles for music’s biggest ...