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Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
[3] [2] [4] The modafinil analogues are of interest in the potential treatment of a condition involving the misuse of stimulant drugs (psychostimulant use disorder or PSUD), as drugs that help increase motivation (pro-motivational agents) to treat motivational disorders, [4] [5] [6] and for treatment of neurodegenerative diseases such as ...
[3] [4] Eugeroics are also often prescribed off-label for the treatment of EDS in idiopathic hypersomnia. [11] In contrast to classical psychostimulants , such as amphetamine and methylphenidate , which are also used in the treatment of these disorders, eugeroics typically do not produce euphoria , and, consequently, have lower misuse potential .
New drugs to treat debilitating menopause symptoms — namely hot flashes — are finally on the market or are in development. But doctors say insurance companies either won’t pay for them or ...
The clinic also spent nearly $100,000 during that period on Provigil, a stimulant that is “55 times more expensive than the generic equivalent,” the report said.
A Phase 3 trial showed that it improved hot flashes in slightly less than half of those who took it: 48% of women on a higher dose and 36% of those on a lower dose reported being much, or ...
Modafinil (Provigil) and pramipexole (Mirapex) have been suggested for treating cognitive dysfunction associated with bipolar depression, but evidence supporting their use is quite limited. [ 25 ] [ 26 ] In addition, riluzole , a glutamatergic drug used in ALS has been studied as an adjunct or monotherapy treatment in bipolar depression, with ...
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