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The deactivated exotoxins are called toxoids and they are not harmful to somatic cells. An exotoxin is a toxin secreted by bacteria. [1] An exotoxin can cause damage to the host by destroying cells or disrupting normal cellular metabolism. They are highly potent and can cause major damage to the host. Exotoxins may be secreted, or, similar to ...
Streptococcal pyrogenic exotoxins also known as erythrogenic toxins, are exotoxins secreted by strains of the bacterial species Streptococcus pyogenes. [ 1 ] [ 2 ] SpeA and speC are superantigens , which induce inflammation by nonspecifically activating T cells and stimulating the production of inflammatory cytokines . [ 3 ]
In addition, stem cell are undifferentiated cells which can develop into a specialized cell and are the earliest type of cell in a cell lineage. [2] Due to the differentiation in function, somatic cells are found only in multicellular organisms, as in unicellular ones the purposes of somatic and germ cells are consolidated in one cell.
Exotoxins are extremely immunogenic and trigger the humoral response (antibodies target the toxin). Exotoxins are also produced by some fungi as a competitive resource. The toxins, named mycotoxins, deter other organisms from consuming the food the fungi colonise. As with bacterial toxins, there is a wide array of fungal toxins.
Genotoxicity is the property of chemical agents that damage the genetic information within a cell causing mutations, which may lead to cancer.While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, but some genotoxic substances are not mutagenic.
Exotoxins are typically proteins with enzymatic activity that interfere with host cells triggering the symptoms associated with the disease. Exotoxins are also relatively specific to the bacteria that produce it; for example, diphtheria toxin is only produced by Corynebacterium diphtheriae bacteria and is required for the diphtheria disease. [3]
It’s estimated that nearly 5% of Americans above the age of 12 live with hypothyroidism, a condition that occurs when the body experiences a deficit of thyroid hormone.. The thyroid gland ...
Streptococcal exotoxins are produced by Streptococcus pyogenes. [7] [8] These toxins share the ability to bind to the major histocompatibility complex proteins of their hosts. A more distant relative of the family is the S. aureus toxic shock syndrome toxin, which shares only a low level of sequence similarity with this group.