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Excessive iron can lead to a condition called hemochromatosis, which may damage organs like the liver, heart and pancreas. Symptoms of iron overload include fatigue, skin discoloration, and joint ...
Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
If excess iron in the heart interferes with its ability to circulate enough blood, a number of problems can occur, including (potentially fatal) congestive heart failure. The condition may be reversible when haemochromatosis is treated and excess iron stores are reduced.
Iron is available over the counter as a single entity supplement in an iron salt form or in combination with vitamin supplements and is commonly used in the treatment of anemias. [ 1 ] [ 2 ] Overdoses on iron can be categorized as unintentional ingestion which is predominantly associated with children or intentional ingestion involving suicide ...
Heart disease is the leading cause of death for both sexes in the U.S., ... In fact, almost 45% of women over age 20 are living with some form of cardiovascular disease. For women in particular ...
During a period of 7½ years, there were 407 cases of heart failure in the group. The risk was found to be 12% to 17% lower for every 70 minutes of light activity (housework, self-care and other ...
Heart disease, liver damage, and kidney failure can result from iron buildup in these organs. [5] Symptoms of sideroblastic anemia usually resemble the common symptoms of anemia. In addition to the symptoms listed above, patients with sideroblastic anemia may experience shortness of breath, heart palpitations, and headache.
Iron malabsorption is a less common cause of iron-deficiency anemia, but many gastrointestinal disorders can reduce the body's ability to absorb iron. [39] There are different mechanisms that may be present. In coeliac disease, abnormal changes in the structure of the duodenum can decrease iron absorption. [40]