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  2. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    Warfarin interacts with many commonly used drugs, and the metabolism of warfarin varies greatly between patients. [27] Some foods have also been reported to interact with warfarin. [27] Apart from the metabolic interactions, highly protein bound drugs can displace warfarin from serum albumin and cause an increase in the INR. [63]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. People admitted to hospital requiring blood thinning were started on an infusion of heparin infusion, which thinned blood ...

  4. Polypharmacy - Wikipedia

    en.wikipedia.org/wiki/Polypharmacy

    When a new drug is prescribed, the risk of interactions increases exponentially. Doctors and pharmacists aim to avoid prescribing medications that interact; often, adjustments in the dose of medications need to be made to avoid interactions. For example, warfarin interacts with many medications and supplements that can cause it to lose its effect.

  5. Direct thrombin inhibitor - Wikipedia

    en.wikipedia.org/wiki/Direct_thrombin_inhibitor

    Ximelagatran showed good efficacy compared with warfarin in several trials in prevention and treatment of deep vein thrombosis and as thromboprophylaxis in atrial fibrillation. [1] Development was stopped by manufacturer AstraZeneca , however, because of reports of liver enzyme derangements and liver failure .

  6. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drugdrug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drugdrug interactions. [2] Drug interactions can be of three kinds ...

  7. Aminoglutethimide - Wikipedia

    en.wikipedia.org/wiki/Aminoglutethimide

    It enhances the metabolism of dexamethasone, so hydrocortisone should be used instead. [8] If the person is taking warfarin, the dosage of warfarin may need to be increased. [8] Alcohol potentiates the central nervous system side effects of AG. [8] Dosages of theophylline, digitoxin, and medroxyprogesterone acetate may need to be increased. [8]

  8. Escitalopram (Lexapro): Everything You Need to Know Before ...

    www.aol.com/escitalopram-lexapro-everything-know...

    It can be caused by certain drug interactions, as well as drinking alcohol while taking a medication like Lexapro. The signs and symptoms of Serotonin Syndrome include: Agitation or restlessness

  9. Vitamin K antagonist - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K_antagonist

    Pindone, chlorophacinone, and diphacinone are used as rodenticides. They are categorised as "first-generation" anticoagulants, and have similar effects as warfarin. They have been largely superseded by second-generation anticoagulants because warfarin-resistant rodents have become more common. [6]

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