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The tablet is pushed against a stationary anvil until it fractures. A reading is taken from a scale indicator. [5] Kraemer Elektronik's tablet testing system was the first automatic tablet hardness testing system for auto-regulation at tablet presses, invented by German mechanical engineer Mr. Norbert Kraemer in Darmstadt, Germany.
A variety of hardness-testing methods are available, including the Vickers, Brinell, Rockwell, Meyer and Leeb tests. Although it is impossible in many cases to give an exact conversion, it is possible to give an approximate material-specific comparison table for steels .
Modern tablet presses reach output volumes of up to 1,700,000 tablets per hour. These huge volumes require frequent in-process quality control for the tablet weight, thickness and hardness. Due to efforts to reduce rejects rates and machine down-time, automated tablet testing devices are used on-line with the tablet press or off-line in the IPC ...
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The basic test requires applying the force in a consistent manner, without shock, and measuring the hardness (depth of the indentation). If a timed hardness is desired, force is applied for the required time and then read. The material under test should be a minimum of 6 mm (0.25 inches) thick. [3]
Friability and abrasion testing is performed in rotating testing drums, designed according to the pharmacopeia. The measured parameter is weight loss before and after testing and tumbling the tablets at a particular time and speed. In the friability test drum tablets are being carried up by a "shovel" and dropped.
A Rockwell hardness tester. The Rockwell hardness test is a hardness test based on indentation hardness of a material. The Rockwell test measures the depth of penetration of an indenter under a large load (major load) compared to the penetration made by a preload (minor load). [1]
The Brinell hardness is designated by the most commonly used test standards (ASTM E10-14 [2] and ISO 6506–1:2005) as HBW (H from hardness, B from brinell and W from the material of the indenter, tungsten (wolfram) carbide). In former standards HB or HBS were used to refer to measurements made with steel indenters.