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The genome of Pseudomonas aeruginosa consists of a relatively large circular chromosome (5.5–6.8 Mb) that carries between 5,500 and 6,000 open reading frames, and sometimes plasmids of various sizes depending on the strain. [11] Comparison of 389 genomes from different P. aeruginosa strains showed that just 17.5% is shared.
Pseudomonas infection refers to a disease caused by one of the species of the genus Pseudomonas. P. aeruginosa is a germ found in the environment and it is an opportunistic human pathogen most commonly infecting immunocompromised patients, such as those with cancer, diabetes, cystic fibrosis, [1] severe burns, AIDS, [2] or people who are very ...
Phage therapy is being used to great effect in the treatment of biofilm infections, especially Pseudomonas aeruginosa and Staphylococcus aureus. [ 102 ] [ 83 ] From 78 recent cases of treatment of biofilm infections, 96% of patients saw clinical improvement using phage therapy, and 52% of patients saw complete symptom relief or a full ...
Pseudomonas aeruginosa is a common bacterial cause of green nail syndrome. Green nail syndrome is caused when the nail is exposed to a bacterial organism, which leads to opportunistic infection. [9] Pseudomonas aeruginosa, the most common cause but not the only one, [10] is frequently found in nature including in water sources, humans, animals ...
Pseudomonas aeruginosa is highly contagious and has displayed resistance to antibiotic treatments, making it difficult to manage effectively. Some strains of Pseudomonas are known to target white blood cells in various mammal species , posing risks to humans, cattle, sheep, and dogs alike.
The combination has activity against many Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa. [4] It is used to treat pelvic inflammatory disease, intra-abdominal infection, pneumonia, cellulitis, and sepsis. [4] It is given by injection into a vein. [5]
Hot tub folliculitis, also called Pseudomonal folliculitis or Pseudomonas aeruginosa folliculitis, is a common type of folliculitis featuring inflammation of hair follicles and surrounding skin. [1]: 272 This condition is caused by an infection of the skin and hair follicles by the bacterium Pseudomonas aeruginosa.
The Pseudomonas exotoxin (or exotoxin A) is an exotoxin produced by Pseudomonas aeruginosa. [1] Vibrio cholerae produces a similar protein called the Cholix toxin 2] It inhibits elongation factor-2. It does so by ADP-ribosylation of EF2 using NAD+. This then causes the elongation of polypeptides to cease.