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Pairwise Comparison: The Pairwise comparison of genomic sequence data is widely utilized in comparative gene prediction. Many studies in comparative functional genomics lean on pairwise comparisons, wherein traits of each gene are compared with traits of other genes across species. his method yields many more comparisons than unique ...
Genetic distance is a measure of the genetic divergence between species or between populations within a species, whether the distance measures time from common ancestor or degree of differentiation. [2] Populations with many similar alleles have small genetic distances. This indicates that they are closely related and have a recent common ancestor.
In quantitative genetics, Q ST is a statistic intended to measure the degree of genetic differentiation among populations with regard to a quantitative trait. It was developed by Ken Spitze in 1993. [1] Its name reflects that Q ST was intended to be analogous to the fixation index for a single genetic locus (F ST).
Predictive genomics is at the intersection of multiple disciplines: predictive medicine, personal genomics and translational bioinformatics.Specifically, predictive genomics deals with the future phenotypic outcomes via prediction in areas such as complex multifactorial diseases in humans. [1]
This comparison of genetic variability within and between populations is frequently used in applied population genetics. The values range from 0 to 1. A zero value implies complete panmixia; that is, that the two populations are interbreeding freely. A value of one implies that all genetic variation is explained by the population structure, and ...
The primary reason for the use of model organisms in research is the evolutionary principle that all organisms share some degree of relatedness and genetic similarity due to common ancestry. The study of taxonomic human relatives, then, can provide a great deal of information about mechanism and disease within the human body that can be useful ...
The degree of hybridization between the spike-ins and the control probes is used to normalize the hybridization measurements for the target probes. Although absolute levels of gene expression may be determined in the two-color array in rare instances, the relative differences in expression among different spots within a sample and between ...
In genetics, the K a /K s ratio, also known as ω or d N /d S ratio, [a] is used to estimate the balance between neutral mutations, purifying selection and beneficial mutations acting on a set of homologous protein-coding genes.