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People with fibromyalgia can also experience insomnia [10] and general hypersensitivity. [11] [12] The causes of fibromyalgia are unknown, with several pathophysiologies proposed. Fibromyalgia was first defined in 1990, with updated criteria in 2011, [4] 2016, [9] and 2019. [12] Fibromyalgia is estimated to affect 2 to 4% of the population. [13]
Wolff's law, developed by the German anatomist and surgeon Julius Wolff (1836–1902) in the 19th century, states that bone in a healthy animal will adapt to the loads under which it is placed. [1] If loading on a particular bone increases, the bone will remodel itself over time to become stronger to resist that sort of loading.
Functional somatic syndrome (FSS) is any of a group of chronic diagnoses with no identifiable organic cause.This term was coined by Hemanth Samkumar. [citation needed] It encompasses disorders such as fibromyalgia, chronic widespread pain, temporomandibular disorder, irritable bowel syndrome, [1] lower back pain, tension headache, atypical face pain, non-cardiac chest pain, insomnia ...
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For example, the body regenerates a full bone within ten years, while non-injured skin tissue is regenerated within two weeks. [2] With injured tissue, the body usually has a different response. This emergency response usually involves building a degree of scar tissue over a time period longer than a regenerative response, as has been proven ...
Malnutrition first causes fat loss but may progress to muscle atrophy in prolonged starvation and can be reversed with nutritional therapy. In contrast, cachexia is a wasting syndrome caused by an underlying disease such as cancer that causes dramatic muscle atrophy and cannot be completely reversed with nutritional therapy.
The number of bones in the human skeletal system is a controversial topic. Humans are born with over 300 bones; however, many bones fuse together between birth and maturity. As a result, an average adult skeleton consists of 206 bones. The number of bones varies according to the method used to derive the count.
Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
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