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Methylamine, also known as methanamine, is an organic compound with a formula of CH 3 NH 2. This colorless gas is a derivative of ammonia , but with one hydrogen atom being replaced by a methyl group .
Free base (freebase, free-base) is a descriptor for the neutral form of an amine commonly used in reference to illicit drugs. The amine is often an alkaloid , such as nicotine , cocaine , morphine , and ephedrine , or derivatives thereof.
Being a base, N-methylaminoethanol forms neutral salts with fatty acids, which are used as surfactants (soaps) with good emulsifying properties and find applications in textile and personal care cleansing products. When bleaching cotton-polyester blends, NMEA is used as a brightener.
Upon exposure to air, it combines with carbon dioxide to form a solid carbonate salt. [20] Phenethylamine is strongly basic, pK b = 4.17 (or pK a = 9.83), as measured using the HCl salt, and forms a stable crystalline hydrochloride salt with a melting point of 217 °C. [10] [21] Its experimental log P is 1.41. [10]
Trimethylamine is a full agonist of human TAAR5, [13] [14] [15] a trace amine-associated receptor that is expressed in the olfactory epithelium and functions as an olfactory receptor for tertiary amines. [15] [16] One or more additional odorant receptors appear to be involved in trimethylamine olfaction in humans as well. [16]
Dimethylamine is a weak base and the pKa of the ammonium CH 3-NH + 2-CH 3 is 10.73, a value above methylamine (10.64) and trimethylamine (9.79). Dimethylamine reacts with acids to form salts, such as dimethylamine hydrochloride, an odorless white solid with a melting point of 171.5 °C.
Amine oxides are surfactants commonly used in consumer products such as shampoos, conditioners, detergents, and hard surface cleaners. [2] Alkyl dimethyl amine oxide (chain lengths C10–C16) is the most commercially used amine oxide. [3]
The synthesis of N-methyltaurine was reported as early as 1878, [4] with methylamine being reacted with the silver salt of 2-chloroethanesulfonic acid. An obvious modification for this reaction is the replacement of the silver salt of 2-chloroethanesulfonic acid by the sodium salt of 2-chloroethanesulfonic acid. [5]