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Oxcarbazepine, sold under the brand name Trileptal among others, is a medication used to treat epilepsy. [ 3 ] [ 5 ] For epilepsy it is used for both focal seizures and generalized seizures . [ 6 ] It has been used both alone and as add-on therapy in people with bipolar disorder who have had no success with other treatments.
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
Trileptal (oxcarbazepine) – an anticonvulsant used as a mood stabilizer; Trintellix (vortioxetine) – an antidepressant of the serotonin modulator and stimulator class; Tegretol (carbamazepine) – an anticonvulsant used as a mood stabilizer; Trilafon (perphenazine)- an antipsychotic used to treat schizophrenia
Gene conversion is the process by which one DNA sequence replaces a homologous sequence such that the sequences become identical after the conversion. [1] Gene conversion can be either allelic , meaning that one allele of the same gene replaces another allele, or ectopic , meaning that one paralogous DNA sequence converts another.
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. [1] It is an active metabolite of oxcarbazepine. [1] [2] In addition, an enantiomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate.
The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study showed that most blood concentrations in breastfed infants of mothers taking carbamazepine, oxcarbazepine, valproate, levetiracetam, and topiramate were quite low, especially in relationship to the mother's level and what the fetal level would have been ...
Adverse effects are similar to oxcarbazepine. The most common ones (more than 10% of patients) are tiredness and dizziness. Other fairly common side effects (1 to 10%) include impaired coordination, gastrointestinal disorders such as diarrhoea, nausea and vomiting, rash (1.1%), and hyponatremia (low sodium blood levels, 1.2%).
ATC code N03 Antiepileptics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
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