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Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
People report using kratom for a variety of reasons, including pain relief, fatigue and to help curb drug withdrawal symptoms, according to the National Institute on Drug Abuse.
Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]
Multiple studies have shown that low-dose naltrexone has promise as a treatment for chronic pain, some autoimmune disorders and cancers. [8] [9] [10] As of 2014, no peer-reviewed studies supporting low-dose naltrexone for multiple sclerosis (MS) have been published. [11] [12] Clinical trials for treatment of fibromyalgia were initiated in 2021 ...
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In the Philippines, where it is most commonly known as sambong, Blumea balsamifera is used in traditional herbal medicine for the common cold and as a diuretic. [1] [2] [3] It is also used for infected wounds, respiratory infections, and stomach pains in Thai and Chinese folk medicine.
Kratom tea made from the dried leaves of the kratom tree. It has opioid-like properties and some stimulant-like effects. [14] [15] St. John's wort tea, the plant has been shown to have antidepressant properties according to a 2017 meta-analysis. [16] Ephedra tea, mainly from the plant Ephedra sinica. [17]
Ketamine has similar efficacy to opioids in a hospital emergency department setting for the management of acute pain and the control of procedural pain. [53] It may also prevent opioid-induced hyperalgesia [54] [55] and postanesthetic shivering. [56] For chronic pain, ketamine is used as an intravenous analgesic, mainly if the pain is ...