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  2. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Although a prospective cohort study of middle-aged women indicated that some flavonoid-rich foods are associated with a reduction in all-cause mortality, frequent grapefruit consumption was associated with a small increase in all-cause mortality, possibly because of the clinically significant drug interactions of the non-flavonoid components. [8]

  3. This Is The Least Healthy Fruit, CDC Says - AOL

    www.aol.com/least-healthy-fruit-cdc-says...

    The least healthy fruit of all of the powerhouse fruits is the white grapefruit, according to the CDC. It scored 10.47 on the agency's ranking, compared to a perfect 100 for watercress .

  4. Can grapefruit boost your immune system and help you lose ...

    www.aol.com/news/grapefruit-boost-immune-system...

    There is no evidence that grapefruit, or any other food, can burn fat, Politi says. “However, as a nutritious, low calorie, satisfying choice, it can be part of a meal plan conducive to weight loss.

  5. What You Need To Know Before Eating Your Daily Grapefruit - AOL

    www.aol.com/know-eating-daily-grapefruit...

    The Health Benefits Of Grapefruit. Water-rich grapefruit contains a variety of nutrients that your body needs. One cup of grapefruit contains over 100% of your daily vitamin C, in addition to ...

  6. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

  7. Grapefruit juice - Wikipedia

    en.wikipedia.org/wiki/Grapefruit_juice

    Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]

  8. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    "There are certain substances in grapefruit juice and grapefruit that may affect the way the body handles a medication," says Leonard. "This can result in fluctuating levels of a medication in the ...

  9. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors , directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors , and their simultaneous consumption results in the overstimulation of the receptor, which can ...

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