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Trazodone, sold under many brand names, [1] is an antidepressant medication, [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
One of these drugs – trazodone hydrochloride – is already licensed for use in humans as an antidepressant. Mallucci said: “The exciting development is that we've bypassed the whole drug discovery pipeline, which can take forever. You don't know what's going to work in humans but it means we don't have to wait 20 years to find something.”
Most but not all values are for human proteins. These drugs act as antagonists or inverse agonists of the 5-HT 2A , α 1 -adrenergic, and H 1 receptors, as partial agonists of the 5-HT 1A receptor, [ 3 ] and as inhibitors of the transporters. mCPP is an antagonist of the 5-HT 2B receptor, an agonist of the 5-HT 1A , [ 3 ] 5-HT 2C , and 5-HT 3 ...
This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.
Saphris – atypical antipsychotic used to treat schizophrenia and bipolar disorder; Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]
Performance-enhancing substances, also known as performance-enhancing drugs (PEDs), [41] are substances that are used to improve any form of activity performance in humans. A well-known example of cheating in sports involves doping in sport , where banned physical performance-enhancing drugs are used by athletes and bodybuilders .
Benzoctamine (Tacitin) – a tetracyclic compound and is closely related to maprotiline, with the two compounds differing only in the length of their side chain, but benzoctamine is not used as an antidepressant and is instead used as an anxiolytic
Nefazodone is a phenylpiperazine compound and is related to trazodone. It has been described as a serotonin antagonist and reuptake inhibitor (SARI) due to its combined actions as a potent antagonist of the serotonin 5-HT 2A and 5-HT 2C receptors and weak serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI).
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261