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A 2017 review of research literature published in the journal Current Psychiatry Reports notes that it’s common for antidepressants to affect sleep (though it didn’t mention sertraline by name).
Sertraline is contraindicated in individuals taking monoamine oxidase inhibitors or the antipsychotic pimozide. Sertraline concentrate contains ethanol and is therefore contraindicated with disulfiram. The prescribing information recommends that treatment of the elderly and patients with liver impairment "must be approached with caution".
Over the course of two years, I was prescribed a variety of different medications for depression, like Zoloft, Celexa, and Cymbalta, until I decided on Cymbalta, which worked well for me.
Duloxetine is one of the most commonly used prescription medications in the U.S. Patients with depression are usually prescribed 40 to 60 milligrams per day, with a potential increase of up to 120 ...
The authors attributed the relationship between severity and efficacy to a reduction of the placebo effect in severely depressed patients, rather than an increase in the effect of the medication. [11] Some researchers have questioned the statistical basis of this study suggesting that it underestimates the effect size of antidepressants. [12] [13]
Although two-thirds of patients will ultimately respond to antidepressant treatment, one-third of patients respond to placebo, [20] and remission is frequently sub-maximal (residual symptoms). In addition to post-treatment relapse, depressive symptoms can even recur in the course of long-term therapy ( tachyphylaxis ).
Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram). Effectiveness and side effect rates can vary between SSRIs. As such, your healthcare provider may suggest ...
The risk of liver damage appears to be only for patients already at risk, unlike the antidepressant nefazodone, which, though rare, can spontaneously cause liver failure in healthy patients. [13] Duloxetine is also approved for major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic neuropathy, chronic musculoskeletal pain ...
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