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Ulcers on your legs and feet. Pale or blue skin, which may be harder to spot on darker skin tones. ... Atherosclerosis in the pelvis and other blood vessel problems are among the potential causes.
Peripheral veinous disease, on the other hand, refers to problems with veins—the vessels that bring the blood back to the heart. [18] The classic symptom is leg pain when walking, which resolves with rest and is known as intermittent claudication. [2]
Swelling of legs, feet, ankles, abdomen, or neck veins. ... Other strokes are not directly caused by heart disease but are related to blood vessel disease (e.g., carotid artery stenosis).
Raynaud’s disease is a rare peripheral vascular syndrome that narrows blood vessels, generally in the hands and feet, due to cold or stressful emotion. [8] It is recognized by the reduction of blood flow to fingers and toes with periodic spasm and results in a drastic color change to white or blue.
The most commonly affected vessels in peripheral vascular disease are the arteries supplying the legs, so when less blood gets to the muscle tissue in the legs, that tissue sees less oxygen and becomes ischemic. Ischemic cells release adenosine, a type of signaling molecule, which is thought to affect nerves in these areas, which is felt as pain.
Atherosclerosis in the aorta and other large blood vessels is a common risk factor, [2] both for thromboembolism and cholesterol embolism. The legs and feet are major impact sites for these types. [2] Thus, risk factors for atherosclerosis are risk factors for arterial embolisation as well: advanced age [1] cigarette smoking [1] [2]
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