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They have been marketed as herbal incense, or "herbal smoking blends", [6] and sold under common names like K2, spice, [8] and synthetic marijuana. [5] They are often labeled "not for human consumption" for liability defense. [ 8 ]
JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
Liquid chromatography (LC) techniques are also possible and, unlike GC methods, can differentiate between the acid and neutral forms of the cannabinoids. There have been systematic attempts to monitor the cannabinoid profile of cannabis over time, but their accuracy is impeded by the illegal status of the plant in many countries.
5F-CUMYL-PINACA (also known as SGT-25 and sometimes sold in e-cigarette form as C-Liquid) [1] is an indazole-3-carboxamide based synthetic cannabinoid. [2] 5F-CUMYL-PINACA acts as a potent agonist for the cannabinoid receptors, with the original patent claiming approximately 4x selectivity for CB 1, having an EC 50 of <0.1 nM for human CB 1 receptors and 0.37 nM for human CB 2 receptors. [3]
A wave of consumer discontent appears to have helped lift him back into the Oval Office, but Trump now faces the task of how to ease voters' frustration. Food inflation soared to a peak of more ...
If you’re stuck on today’s Wordle answer, we’re here to help—but beware of spoilers for Wordle 1257 ahead. Let's start with a few hints.
Butyl nitrite is the organic compound with the formula CH 3 (CH 2) 3 ONO. It is an alkyl nitrite made from n-butanol.Butyl nitrite is used recreationally as poppers.Synonyms include 1-butyl nitrite, n-butyl nitrite and nitrous acid butyl ester.
An MTA cleaner allegedly slashed a man who confronted him for pouring bleach near the spot where he’d been sleeping on a Brooklyn subway platform early Monday, cops and sources said.