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[150] [151] In May 2016, the Psychoactive Substances Act was enacted, which made illegal the production, distribution, sale, supply, and possession in correctional institutions of any substance for human consumption with psychoactive effects. [152] This stopped the open sale of synthetic cannabinoids in head shops, although they are still found ...
5F-CUMYL-PINACA (also known as SGT-25 and sometimes sold in e-cigarette form as C-Liquid) [1] is an indazole-3-carboxamide based synthetic cannabinoid. [2] 5F-CUMYL-PINACA acts as a potent agonist for the cannabinoid receptors, with the original patent claiming approximately 4x selectivity for CB 1, having an EC 50 of <0.1 nM for human CB 1 receptors and 0.37 nM for human CB 2 receptors. [3]
5F-APINACA (also known as A-5F-PINACA, [3] 5F-AKB-48 or 5F-AKB48) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. [4] [5] Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as despite not being disclosed as ...
Bath salts usually contain cathinones, typically methylenedioxypyrovalerone (MDPV, also known as "monkey dust", although this term can refer to MDPHP as well [8]), methylone or mephedrone; however, the chemical composition varies widely [6] [9] and products labeled with the same name may also contain derivatives of pyrovalerone or pipradrol.
The RealReal used data from U.S. Customs and Border Protection and Census records to highlight the proliferation of counterfeit goods in e-commerce.
JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
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