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  2. Muscle fatigue - Wikipedia

    en.wikipedia.org/wiki/Muscle_fatigue

    Muscle fatigue is not the same as muscle weakness, though weakness is an initial symptom. Despite a normal amount of force being generated at the start of activity, once muscle fatigue has set in and progressively worsens, if the individual persists in the exercise they will eventually lose their hand grip, or become unable to lift or push with ...

  3. Myasthenia gravis - Wikipedia

    en.wikipedia.org/wiki/Myasthenia_gravis

    The muscle weakness that worsens with activity (abnormal muscle fatigue) in myasthenia gravis [66] is a symptom shared by other neuromuscular diseases. Most of the metabolic myopathies , such as McArdle disease (GSD-V), have abnormal muscle fatigue rather than fixed muscle weakness.

  4. Muscle weakness - Wikipedia

    en.wikipedia.org/wiki/Muscle_weakness

    The insufficiency of energy, i.e. sub-optimal aerobic metabolism, generally results in the accumulation of lactic acid and other acidic anaerobic metabolic by-products in the muscle, causing the stereotypical burning sensation of local muscle fatigue, though recent studies have indicated otherwise, actually finding that lactic acid is a source ...

  5. Delayed onset muscle soreness - Wikipedia

    en.wikipedia.org/wiki/Delayed_onset_muscle_soreness

    Delayed onset muscle soreness (DOMS) is the pain and stiffness felt in muscles after unaccustomed or strenuous exercise. The soreness is felt most strongly 24 to 72 ...

  6. Benign fasciculation syndrome - Wikipedia

    en.wikipedia.org/wiki/Benign_fasciculation_syndrome

    The main symptom of benign fasciculation syndrome is focal or widespread involuntary muscle activity (fasciculation). [1] The benign twitches usually have a constant location. [2] Other common symptoms are generalized fatigue or weakness, paraesthesia or numbness, and muscle cramping or spasms. [1]

  7. Myopathy - Wikipedia

    en.wikipedia.org/wiki/Myopathy

    This meaning implies that the primary defect is within the muscle, as opposed to the nerves ("neuropathies" or "neurogenic" disorders) or elsewhere (e.g., the brain). This muscular defect typically results in myalgia (muscle pain), muscle weakness (reduced muscle force), or premature muscle fatigue (initially normal, but declining muscle force).

  8. Muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Muscular_Dystrophy

    It links the muscle membrane to the thin muscular filaments within the cell. Dystrophin is an integral part of the muscular structure. An absence of dystrophin can cause impairments: healthy muscle tissue can be replaced by fibrous tissue and fat, causing an inability to generate force. [4] Respiratory and cardiac complications can occur as well.

  9. Spinal and bulbar muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Spinal_and_bulbar_muscular...

    Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.