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Metformin Side Effects. Metformin (and the brand-name versions, Riomet and Glucophage) isn’t used by people with type 1 diabetes, an autoimmune disorder wherein the body does not make insulin.
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [76] [81] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
It can take a little while for metformin to change the numbers on the scale. Weight loss is a slow-and-steady game. ... Metformin can also cause a vitamin B12 deficiency, which may be linked with ...
Taking metformin may cause unpleasant side effects like diarrhea, nausea, and an upset stomach. Taking it with food can reduce the risk.
Diurnal mood variation or morning depression is a prominent [1] depression symptom characterized by gradual mood improvement through the day, reaching its peak sometime after twilight. While the main form of diurnal mood variation presents itself as described, a reversed form, with a worsening of mood towards the evening, also exists. [ 2 ]
The term idiopathic postprandial syndrome, which literally means a syndrome that occurs after eating (postprandial) and is of unknown cause (), was coined in an attempt to reserve the term hypoglycemia for those conditions in which low glucose levels could be demonstrated. [1]
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...
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