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  2. Hypoxic pulmonary vasoconstriction - Wikipedia

    en.wikipedia.org/wiki/Hypoxic_pulmonary...

    This contrasts with the classical explanation of HPV which presumes that hypoxia is sensed at the pulmonary artery smooth muscle cell itself. Specialized epithelial cells (neuroepithelial bodies) that release serotonin have been suggested to contribute to hypoxic pulmonary venoconstriction. [8]

  3. Hypoxia (medicine) - Wikipedia

    en.wikipedia.org/wiki/Hypoxia_(medicine)

    By contrast, in the lungs, the response to hypoxia is vasoconstriction. This is known as hypoxic pulmonary vasoconstriction, or "HPV", and has the effect of redirecting blood away from poorly ventilated regions, which helps match perfusion to ventilation, giving a more even oxygenation of blood from different parts of the lungs. [81]

  4. Tumor hypoxia - Wikipedia

    en.wikipedia.org/wiki/Tumor_hypoxia

    Tumor stroma and extracellular matrix in hypoxia. Tumor hypoxia is the situation where tumor cells have been deprived of oxygen.As a tumor grows, it rapidly outgrows its blood supply, leaving portions of the tumor with regions where the oxygen concentration is significantly lower than in healthy tissues.

  5. HPV-positive oropharyngeal cancer - Wikipedia

    en.wikipedia.org/wiki/HPV-positive_oropharyngeal...

    HPV+OPC presents in one of four ways: as an asymptomatic abnormality in the mouth found by the patient or a health professional such as a dentist; with local symptoms such as pain or infection at the site of the tumor; with difficulties of speech, swallowing, and/or breathing; or as a swelling in the neck (if the cancer has spread to lymph nodes).

  6. High-altitude pulmonary edema - Wikipedia

    en.wikipedia.org/wiki/High-altitude_pulmonary_edema

    Hypoxic pulmonary vasoconstriction (HPV) occurs diffusely, leading to arterial vasoconstriction in all areas of the lung. This is evidenced by the appearance of "diffuse," "fluffy," and "patchy" infiltrates described on imaging studies of climbers with known HAPE.

  7. HPV-associated oropharyngeal cancer awareness and prevention

    en.wikipedia.org/wiki/HPV-associated_oro...

    Human papillomavirus (HPV)-associated oropharyngeal cancer awareness and prevention is a vital concept from a public and community health perspective. HPV is the sexually transmitted virus that is known to be the cause of genital warts. There are currently more than 100 different strains of HPV, half of which can cause genital infections. [1]

  8. Hypoxia-activated prodrug - Wikipedia

    en.wikipedia.org/wiki/Hypoxia-activated_prodrug

    It is believed that tumor hypoxia contributes significantly to treatment failure and relapse among cancer patients because cells in the hypoxic zones of solid tumors resist traditional chemotherapy for at least two reasons: first, most antitumor agents cannot penetrate beyond 50-100 micrometers from capillaries, [1] thereby never reaching those ...

  9. Human papillomavirus infection - Wikipedia

    en.wikipedia.org/wiki/Human_papillomavirus_infection

    Researchers looking for HPV among 1,633 lung cancer patients and 2,729 people without the lung disease found that people with lung cancer had more types of HPV than noncancer patients did, and among lung cancer patients, the chances of having eight types of serious HPV were significantly increased. [81]

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