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Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure in the arteries of the lungs. [7] Symptoms include shortness of breath, fainting, tiredness, chest pain, swelling of the legs, and a fast heartbeat. [7] [1] The condition may make it difficult to exercise. [7] Onset is typically gradual. [8]
A pulmonary artery wedge pressure being less than 15 mmHg (also measured by right heart catheterization) excludes post-capillary bed (in the veins distal to the capillary bed) pulmonary hypertension. Pulmonary arterial hypertension is a subgroup of pulmonary hypertension and is categorized as World Health Organization as group 1. [3]
pulmonary regurgitation murmur in patients with pulmonary hypertension secondary to mitral stenosis Grey Turner's sign: George Grey Turner: surgery: retroperitoneal hemorrhage: flank ecchymosis Griffith's sign: Alexander Hill Griffith, Scottish Ophthalmologist, Manchester (1858–1937) endocrinology: Graves' ophthalmopathy (needed)
An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors. Three main kinds of ERAs exist: Dual ET Receptor Antagonists, which affect both endothelin A (ET A) and B receptors (ET B) [1] aprocitentan, bosentan, macitentan, tezosentan; Selective ET A Receptor Antagonists, which affect endothelin A receptors
Bosentan, sold under the brand name Tracleer among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery hypertension (PAH). [4] [5] Bosentan is available as film-coated tablets (62.5 mg or 125 mg) or as dispersable tablets for oral suspension (32 mg). [4]
Iloprost, sold under the brand name Ventavis among others, is a medication used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon, frostbite, and other conditions in which the blood vessels are constricted and blood cannot flow to the tissues. [4] Iloprost is a prostacyclin mimetic. [1]
This is a list of products and services provided by Johnson & Johnson (J&J). ... Pulmonary hypertension therapies Uptravi [77] Opsumit [78] Veletri [79] Tracleer [80]
Treprostinil, sold under the brand names Remodulin for infusion, Orenitram for oral, and Tyvaso for inhalation, is a vasodilator that is used for the treatment of pulmonary arterial hypertension. [6] Treprostinil was approved for use in the United States in May 2002. [7]
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