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Hydroxyzine (Atarax) is an antihistamine originally approved for clinical use by the FDA in 1956. Hydroxyzine has a calming effect which helps ameliorate anxiety. Hydroxyzine efficacy is comparable to benzodiazepines in the treatment of generalized anxiety disorder. [41]
They can also help to promote sleep — a common difficulty for people with anxiety. Hydroxyzine, sold under the brand name Vistaril, is occasionally used as a short-term treatment for anxiety.
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). [8] It is used either by mouth or injection into a muscle. [8] Hydroxyzine works by blocking the effects of histamine. [9]
Hydroxyzine: 25–100 mg 2 hours 20 hours ADH, CYP3A4, others No Doxepin: 3–6 mg 2–3 hours 17 hours c: CYP2D6, others No (at low doses) Mirtazapine: 7.5–15 mg 2 hours 20–40 hours CYP2D6, others No Quetiapine e: 25–200 mg 1.5 hours 7 hours d: CYP3A4 No (at low doses) Footnotes: a = For sleep/sedation. b = In adults.
This is a list of investigational anxiolytics, or anxiolytics that are currently under development for clinical use but are not yet approved.Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
Deramciclane (EGIS-3886) is a non-benzodiazepine-type anxiolytic drug to treat various types of anxiety disorders. [1] Deramciclane is a unique alternative to current anxiolytics on the market because it has a novel chemical structure and target.
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