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2. Nortriptyline - Wikipedia

   en.wikipedia.org/wiki/Nortriptyline

   Nortriptyline is an active metabolite of amitriptyline by demethylation in the liver. Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [36] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [37]

3. Tricyclic antidepressant overdose - Wikipedia

   en.wikipedia.org/wiki/Tricyclic_antidepressant...

   Most are non-toxic at less than 5 mg/kg except for desipramine, nortriptyline, and trimipramine, which are generally non-toxic at less than 2.5 mg/kg. [5] [2] In small children one or two pills can be fatal. [6] An electrocardiogram (ECG) should be included in the assessment when there is concern of an overdose. [2]

4. Tricyclic antidepressant - Wikipedia

   en.wikipedia.org/wiki/Tricyclic_antidepressant

   However, symptoms may take several hours to appear if a mixed overdose has caused delayed gastric emptying. Many of the initial signs are those associated to the anticholinergic effects of TCAs such as dry mouth, blurred vision, urinary retention, constipation, dizziness, and emesis (or vomiting).

5. Amitriptyline - Wikipedia

   en.wikipedia.org/wiki/Amitriptyline

   It is metabolized to nortriptyline, a stronger norepinephrine reuptake inhibitor, further augmenting amitriptyline's effects on norepinephrine reuptake (see table in this section). Amitriptyline additionally acts as a potent inhibitor of the serotonin 5-HT 2A , 5-HT 2C , the α 1A -adrenergic , the histamine H 1 and the M 1 -M 5 muscarinic ...

6. Can Lexapro Cause Weight Loss? What to Know - AOL

   www.aol.com/lexapro-cause-weight-loss-know...

   For example, another study published in the International Journal of Neuropsychopharmacology in 2011 compared the effects of escitalopram and nortriptyline, a tricyclic antidepressant, on the body ...

7. The Best Time of Day To Take Your Blood Pressure Meds To ...

   www.aol.com/best-time-day-blood-pressure...

   There isn't a precise time of day to take blood pressure medication if you're trying to lower your heart attack risk. Traditionally, however, doctors have recommended people take blood pressure ...

8. Onset of action - Wikipedia

   en.wikipedia.org/wiki/Onset_of_action

   A few drugs such as alcohol are absorbed by the lining of the stomach, and therefore tend to take effect much more quickly than the vast majority of oral medications which are absorbed in the small intestine. Gastric emptying time can vary from 0 to 3 hours, [2] and therefore plays a major role in onset of action for orally administered drugs ...

9. Is There a "Best Time" to Take Metformin? - AOL

   www.aol.com/best-time-metformin-115700262.html

   Well, there’s no magic time, but you should take metformin at the same time each day and with food to avoid gastrointestinal side effects. If you’re taking extended-release metformin tablets ...