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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [11] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [11]
These precautions should remain in place among those in hospital for at least 2 days after the diarrhea has stopped. [69] Bleach wipes containing 0.55% sodium hypochlorite have been shown to kill the spores and prevent transmission. [70] Installing lidded toilets and closing the lid prior to flushing also reduces the risk of contamination. [71]
Amoebiasis in tissues is treated with either metronidazole, tinidazole, nitazoxanide, dehydroemetine or chloroquine. Luminal infection is treated with diloxanide furoate or iodoquinoline. [2] Effective treatment against all stages of the disease may require a combination of medications. [2]
metronidazole 500–750 mg three times a day for 5–10 days; tinidazole 2g once a day for 3 days is an alternative to metronidazole; Doses for children are calculated by body weight and a pharmacist should be consulted for help.
The drug must not be taken by pregnant women, because tetracycline is known to cause tooth and bone defects in unborn children. It is also contraindicated in breastfeeding women, children up to 12 years of age, and by patients with impaired liver or renal (kidney) function, because no studies in such persons have been conducted.
In these cases it is often used in combination with metronidazole, which provides coverage for anaerobic pathogens. [7] complicated urinary tract infections, including acute pyelonephritis, in adults. hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. [11]
In 1993, the successful treatment of cutaneous amebiasis in a 7-year-old girl with dehydroemetine and metronidazole in Mexico. [3] A double-blind study of oral dehydroemetine in the treatment of amoebiasis performed at St. Mary's Hospital, Catholic Medical College, Seoul, Republic of Korea in 1973-1974 showed dehydroemetine treatment was effective.
Metronidazole: This is an antimicrobial effective against some protozoa and strict anaerobes. In the UK, it has effective use in dentistry as it is the primary drug prescribed for acute ulcerative gingivitis. It is also sometimes used either alongside penicillin or alone against dentoalveolar infections with the advantage of having a low ...