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Bartolomei was an undergraduate student at the University of Maryland, College Park, where she majored in biochemistry. [1] She was the first member of her family who graduated from college. [2] Her doctoral research considered mouse RNA polymerase. [3]
Although Charlesworth initially studied biochemistry, genetic variation played a significant role from the beginning her research. [6] Charlesworth obtained her doctorate at Cambridge University in 1968 with her thesis focusing on the quantitative genetics of mice, specifically the extent of genetic variation in the blood glucose levels across ...
There, she was able to choose her own research topics. She used nuclear magnetic resonance to investigate the reaction of phosphorus with ATP, revealing considerable information about the biochemistry of ATP, [3] including the structure of ATP, oxidative phosphorylation and role of divalent ions in the enzymatic conversion of ATP and ADP. [12]
Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics. [ 2 ] A humanized mouse or a humanized mouse model is one that has been xenotransplanted with human cells and/or engineered to express human gene products, so as to be utilized for gaining relevant insights in the in vivo context ...
Paola A. Marignani is a scientist and Full Professor at Dalhousie University in the Faculty of Medicine, Department of Biochemistry and Molecular Biology. [1] She is best known for her research on the tumor suppressor kinase LKB1, [2] and its role in regulating the chromatin remodeling protein SMARCA4 and modeling metabolic processes in breast and lung cancers.
Rebeca Gerschman (June 19, 1903 – April 4, 1986) was an Argentinian biologist and physiologist who received a Ph.D. in Biochemistry and Pharmacy from the University of Buenos Aires. Known for her advances in the field of biochemistry , she was the first scientist to propose—in 1954—that free radicals contributed to oxygen toxicity and ...
After graduating she switched focus to biochemistry and molecular biology, and spent a year at Columbia University in New York studying biology (1971–72). Her PhD from the Massachusetts Institute of Technology , supervised by Malcolm Gefter, was on DNA replication (1976).
Vadim Gladyshev's primary research focuses on understanding the mechanisms behind aging, lifespan control, and rejuvenation. His work spans various dimensions of biology, including selenium biochemistry and redox biology, but is most notably recognized for his contributions to the study of longevity and the aging process.