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  2. Acute liver failure in adults: Etiology, clinical ... - UpToDate

    www.uptodate.com/contents/acute-liver-failure-in-adults-etiology-clinical...

    Acute liver failure refers to the development of severe acute liver injury with impaired synthetic function (INR of ≥1.5) and altered mental status in a patient without cirrhosis or preexisting liver disease . A commonly used cutoff to define acute liver failure is an illness duration of <26 weeks.

  3. Acute liver failure - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/acute-liver-failure/symptoms-causes/syc...

    Acute liver failure is loss of liver function that happens quicklyin days or weeksusually in a person who has no preexisting liver disease. It's most often caused by a hepatitis virus or drugs, such as acetaminophen.

  4. Liver Failure: Causes, Symptoms, Treatments, Tests & More - WebMD

    www.webmd.com/digestive-disorders/digestive-diseases-liver-failure

    Liver failure happens when your liver starts to shut down. This is usually because it's become damaged and can't be repaired. It's a life-threatening condition that demands urgent medical care....

  5. Acute Liver Failure - StatPearls - NCBI Bookshelf

    www.ncbi.nlm.nih.gov/books/NBK482374

    Acute liver failure is defined as severe acute liver injury for fewer than twenty-six weeks duration with encephalopathy and impaired synthetic function (INR of 1.5 or higher) in a patient without cirrhosis or preexisting liver disease.

  6. Liver problems - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/liver-problems/symptoms-causes/syc-20374502

    Liver problems that can occur include fatty liver disease and cirrhosis. The liver and its cells, as seen through a microscope, change greatly when a liver becomes fatty or cirrhotic. Liver disease doesn't always cause symptoms that can be seen or felt.

  7. Liver Disease: Signs & Symptoms, Causes, Stages, Treatment

    my.clevelandclinic.org/health/diseases/17179-

    Liver failure. Stage 1: Hepatitis. Hepatitis means inflammation in your liver tissues. Inflammation is your liver’s response to injury or toxicity. It’s an attempt to purge infections and start the healing process.

  8. Hepatic Failure - StatPearls - NCBI Bookshelf

    www.ncbi.nlm.nih.gov/books/NBK538227

    Acute liver failure (ALF) is a complex clinical syndrome characterized by elevated liver biochemistry, coagulopathy, and hepatic encephalopathy without underlying chronic liver disease. The most frequently used classification is the one that O'Grady and collaborators proposed which divides liver failure into 3 categories based on the interval ...

  9. Acute Liver Failure: Symptoms, Causes, Diagnosis, Treatment - ...

    www.healthline.com/health/acute-liver-failure

    Acute liver failure is a medical emergency that can cause life threatening complications. It’s most commonly caused by drug overdose in the United States, with acetaminophen being the...

  10. Acute liver failure (ALF) is a rare, life-threatening, potentially reversible condition with a rapid decline in hepatic function characterised by jaundice, coagulopathy (INR >1.5), and hepatic encephalopathy in patients with no evidence of prior liver disease.

  11. Acute Liver Failure | New England Journal of Medicine

    www.nejm.org/doi/full/10.1056/NEJMra1208937

    Acute liver failure is a rare but life-threatening critical illness requiring intensive care. This article reviews common causes, diagnostic approaches, and therapeutic...