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Mitragynine toxicity in humans is largely unknown, as animal studies show significant species-specific differences in mitragynine tolerance. [5] Mitragynine toxicity in humans is rarely reported although specific examples of seizures and liver toxicity in kratom consumers have been reported.
This is an accepted version of this page This is the latest accepted revision, reviewed on 29 January 2025. Plant species, recreational drug (kratom) Mitragyna speciosa Conservation status Least Concern (IUCN 3.1) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Asterids Order: Gentianales Family: Rubiaceae Genus: Mitragyna Species: M ...
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
The brain may contain higher -- and more significant -- amounts of microplastics than other organs in the body, according to a new study. Researchers from the University of New Mexico Health ...
There's nothing our pets love more than a huge bowl of the best cat food or dog food and we all know what they get like when that bowl runs dry! We have a feeling one of the first things our pets ...
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An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...
My first pregnancy and postpartum experience were challenging, as I struggled with anxiety and the significant identity change that comes with birthing and raising a human. To cope and adapt, I ...