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Reactive airway disease (RAD) is an informal label that physicians apply to patients with symptoms similar to those of asthma. [1] An exact definition of the condition does not exist. [ 1 ] [ 2 ] Individuals who are typically labeled as having RAD generally have a history of wheezing, coughing, dyspnea , and production of sputum that may or may ...
Bronchial hyperresponsiveness is a hallmark of asthma but also occurs frequently in people with chronic obstructive pulmonary disease (COPD). [2] In the Lung Health Study, bronchial hyperresponsiveness was present in approximately two-thirds of patients with non-severe COPD, and this predicted lung function decline independently of other ...
Inflamed airways are more hyper-reactive, and will be more prone to bronchospasm. The " hygiene hypothesis " postulates that in early life, an imbalance in the regulation of these T H cell types leads to a long-term domination of the cells involved in allergic responses over those involved in fighting infection.
Airway remodelling is observed, but it is unknown whether these represent harmful or beneficial changes. [278] More recent data find that severe asthma can result in airway remodelling and the "asthma with chronic obstructive pulmonary disease syndrome (ACOS)" that has a poor prognosis. [279]
It is the sum of changes that occur in the airways of some asthmatic people compared to people without the disease. [1] [2] Asthma is characterised, in part, by recurrent episodes of reversible airway obstruction; however, in some patients, a degree of irreversible airway obstruction develops over time, leading to lung function decline and ...
493 Asthma. 493.0 Extrinsic asthma; 493.1 Intrinsic asthma; 493.2 Chronic obstructive asthma; 494 Bronchiectasis; 495 Extrinsic allergic alveolitis; 496 Chronic airway obstruction, not elsewhere classified 496.0 COPD, Not Otherwise Specified
Reactive airways dysfunction syndrome (RADS) is a severe form of irritant induced asthma where respiratory symptoms usually develop in the minutes or hours after a single accidental inhalation of a high concentration of irritant gas, aerosol, vapor, or smoke. [3]
If a clinician is concerned that reactive airway disease or asthma may be a component of the illness, a bronchodilator may be administered. [9] Anticholinergic inhalers, such as ipratropium bromide, have a modest short-term effect at best and are not recommended for treatment. [20] [49] [50]
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