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For example, uncaging glutamate is useful for finding excitatory connections between neurons, since the uncaged glutamate mimics the natural synaptic activity of one neuron impinging upon another. The other major photostimulation method is the use of light to activate a light-sensitive protein such as rhodopsin , which can then excite the cell ...
Concerns have been raised in the literature about brain stimulation techniques that rely upon low-level (low-power) lasers and light-emitting diodes (LEDs). The transcranial photobiomodulation or transcranial low level light therapy is limited in neuromodulation due to several reasons: An excessive dose of radiation can be harmful. [22]
Neurotechnology encompasses any method or electronic device which interfaces with the nervous system to monitor or modulate neural activity. [1] [2]Common design goals for neurotechnologies include using neural activity readings to control external devices such as neuroprosthetics, altering neural activity via neuromodulation to repair or normalize function affected by neurological disorders ...
Another most recent example is the electrical stimulation of the middle temporal (MT) area of primary visual cortex to bias perception. In particular, the directionality of motion is represented in a regular way in the MT area. They presented monkeys with moving images on screen and monkey throughput was to determine what the direction is.
A thalamic stimulator is a medical device that can suppress tremors, such as those caused by Parkinson's disease or essential tremor. It was approved for use by the Food and Drug Administration (FDA) on August 4, 1997. Installation is invasive, so it is typically only used when the tremors are incapacitating, and medication is ineffective.
Delivery devices must be biocompatible and stable in vivo. Some examples include osmotic pumps, silicone reservoirs, polymer matrices, and microspheres. Gene therapy techniques have also been studied to provide long-term production of growth factors and could be delivered with viral or non-viral vectors such as lipoplexes.
Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain–computer interfaces. (Brain–computer interface research also includes technology such as EEG arrays that allow interface between mind and machine but do not require direct implantation of a device.)
Functional near-infrared spectroscopy (fNIRS) is an optical brain monitoring technique which uses near-infrared spectroscopy for the purpose of functional neuroimaging. [1] Using fNIRS, brain activity is measured by using near-infrared light to estimate cortical hemodynamic activity which occur in response to neural activity.