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  2. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects. [11] [2] Diphenhydramine is also a potent anticholinergic. [12]

  3. Antihistamine - Wikipedia

    en.wikipedia.org/wiki/Antihistamine

    Different studies have reported on antihistamine use in children, with various studies finding evidence that certain antihistamines could be used by children 2 years of age, and other drugs being safer for younger or older children. [1]

  4. Actifed - Wikipedia

    en.wikipedia.org/wiki/Actifed

    The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...

  5. Benadryl - Wikipedia

    en.wikipedia.org/wiki/Benadryl

    [2] Benadryl Allergy is widely used as a sleep aid among adults. While it is not marketed as an over-the-counter (OTC) sleeping aid, most versions of Benadryl contain diphenhydramine, a drug with sedative properties. [6] Diphenhydramine (Benadryl) has also been used by parents to help improve their infant's sleep habits.

  6. Promethazine - Wikipedia

    en.wikipedia.org/wiki/Promethazine

    Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...

  7. Hydroxyzine - Wikipedia

    en.wikipedia.org/wiki/Hydroxyzine

    [52] [53] In rats, less than 2% of the drug is excreted unchanged. [53] The time to reach maximum concentration (T max) of hydroxyzine is about 2.0 hours in both adults and children and its elimination half-life is around 20.0 hours in adults (mean age 29.3 years) and 7.1 hours in children.

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