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Closed-head injuries are the leading cause of death in children under 4 years old and the most common cause of physical disability and cognitive impairment in young people. [ 1 ] [ 2 ] Overall, closed-head injuries and other forms of mild traumatic brain injury account for about 75% of the estimated 1.7 million brain injuries that occur ...
The ultimate consequence of cytotoxic edema is the oncotic death of neurons. [1] The swelling of the individual cells of the brain is the main distinguishing characteristic of cytotoxic edema, as opposed to vasogenic edema, wherein the influx of fluid is typically seen in the interstitial space rather than within the cells themselves. [20]
SBS is the leading cause of fatal head injuries in children under two, [11] with a risk of death of about 25%. [3] The most common symptoms include retinal bleeds , multiple fractures of the long bones , and subdural hematomas (bleeding in the brain). [ 14 ]
TBI is a leading cause of death and disability around the globe [8] and presents a major worldwide social, economic, and health problem. [10] It is the number one cause of coma, [169] it plays the leading role in disability due to trauma, [76] and is the leading cause of brain damage in children and young adults. [15]
Radiation and chemotherapy can lead to brain tissue damage by disrupting or stopping blood flow to the affected areas of the brain. This damage can cause long term effects such as but not limited to; memory loss, confusion, and loss of cognitive function. The brain damage caused by radiation depends on where the brain tumor is located, the ...
These factors cause the brain to swell with fluid, resulting in severe impairment. [15] If the swelling is untreated, it causes death by brain herniation. [4] The brain swelling is likely a result of vasogenic edema, the penetration of the blood–brain barrier by fluids. [16] This process has been observed in MRI studies.
An increase in pressure, most commonly due to head injury leading to intracranial hematoma or cerebral edema, can crush brain tissue, shift brain structures, contribute to hydrocephalus, cause brain herniation, and restrict blood supply to the brain. [13] It is a cause of reflex bradycardia. [14]
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.