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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger-Ellison syndrome . [ 4 ]
These infections can include Helicobacter pylori due to this species not favouring an acid environment, leading to an increased risk of ulcers and gastric cancer risk in genetically susceptible patients. [48] PPI use in people who have received attempted H. pylori eradication may also be associated with an increased risk of gastric cancer. [49]
Cancer was traditionally treated with surgery, heat, or herbal (chemical) therapies. 2600 BC – Egyptian physician Imhotep diagnosed several types of tumour and therapies for them. According to the Ebers medical papyrus, hard tumours were treated by placing a poultice near the tumour, followed by local incision. [ 1 ]
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
The French pharmaceutical company Sanofi says it has reached an agreement to resolve 4,000 cases in the U.S., in which plaintiffs are linking the discontinued heartburn drug Zantac — and its ...
This study was a retrospective, case-control study that compared smoking habits of 684 individuals with bronchogenic carcinoma to those without the condition. [12] The survey included questions about smoking: starting age, 20 year tobacco consumption, brands used; as well as inquires about exposure to hazardous agents in the workplace, alcohol use, and causes of death for family members.
September 24, 2024 at 12:00 PM. Alcohol use accounts for the development of 5.4% all cancer cases in the United States, according to a new expert report. Susan Brooks-Dammann/ Stocksy. While there ...
Zantac was first marketed in 1981, [7] and it was described in 1989 as "one of the most expensive drugs on the market", [8] and "the world's biggest-selling prescription drug". [9] Addiction to taking it ("a habit") was how some of its users described Zantac. [10] The focus of Glaxo, its manufacturer, was to gain market share "from Zantac ...