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Benadryl Allergy. Benadryl Allergy is the name of a Benadryl product found in the United States and Canada. It is an antihistamine drug used to relieve allergies. Its active ingredient is diphenhydramine, a first-generation antihistamine. It is known to be sedative, making drowsiness a common side effect.
Diphenhydramine, while traditionally known as an antagonist, acts primarily as an inverse agonist of the histamine H 1 receptor. [86] It is a member of the ethanolamine class of antihistaminergic agents. [45] By reversing the effects of histamine on the capillaries, it can reduce the intensity of allergic symptoms.
Cyproheptadine is a very potent antihistamine or inverse agonist of the H 1 receptor. At higher concentrations, it also has anticholinergic, antiserotonergic, and antidopaminergic activities. Of the serotonin receptors, it is an especially potent antagonist of the 5-HT 2 receptors.
Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system. [1][2] These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells.
The pressure difference causes the mucosal lining of the sinuses to become swollen and submucosal bleeding follows with further difficulties ventilating the sinus, especially if the orifices are involved. Ultimately fluid or blood will fill the space. In most cases of sinus barotrauma, localized pain to the frontal area is the predominant symptom.
Sinusitis (or rhinosinusitis) is defined as an inflammation of the mucous membrane that lines the paranasal sinuses and is classified chronologically into several categories: [22] Acute sinusitis – A new infection that may last up to four weeks and can be subdivided symptomatically into severe and nonsevere.
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