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Triphenyl phosphate exhibits low acute toxicity by dermal or oral contact. [3] However, an increasing number of studies have linked exposure to TPhP with reproductive and developmental toxicity, neurotoxicity, metabolic disruption, endocrine effects, and genotoxicity. [6] [8] [9] TPhP has also been found to induce significant estrogenic activity.
Triphenylphosphine (IUPAC name: triphenylphosphane) is a common organophosphorus compound with the formula P(C 6 H 5) 3 and often abbreviated to P Ph 3 or Ph 3 P. It is versatile compound that is widely used as a reagent in organic synthesis and as a ligand for transition metal complexes, including ones that serve as catalysts in organometallic chemistry.
Triphenylphosphine oxide (often abbreviated TPPO) is the organophosphorus compound with the formula OP(C 6 H 5) 3, also written as Ph 3 PO or PPh 3 O (Ph = C 6 H 5).It is one of the more common phosphine oxides.
Tricresyl phosphate (TCP), is a mixture of three isomeric organophosphate compounds most notably used as a flame retardant. [1] Other uses include as a plasticizer in manufacturing for lacquers and varnishes and vinyl plastics and as an antiwear additive in lubricants. Pure tricresyl phosphate is a colourless, viscous liquid, although ...
A metal-phosphine complex is a coordination complex containing one or more phosphine ligands. Almost always, the phosphine is an organophosphine of the type R 3 P (R = alkyl, aryl).
Triphenyl phosphite ozonide (TPPO) is a chemical compound with the formula PO 3 (C 6 H 5 O) 3 that is used to generate singlet oxygen. [ 1 ] [ 2 ] When TPPO is mixed with amines , the ozonide breaks down into singlet oxygen and leaves behind triphenyl phosphite . [ 2 ]
Triphenyl phosphite is the organophosphorus compound with the formula P(OC 6 H 5) 3. It is a colourless viscous liquid. It is a colourless viscous liquid. Preparation
The reaction mechanism of the Mitsunobu reaction is fairly complex. The identity of intermediates and the roles they play has been the subject of debate. Initially, the triphenyl phosphine (2) makes a nucleophilic attack upon diethyl azodicarboxylate (1) producing a betaine intermediate 3, which deprotonates the carboxylic acid (4) to form the ion pair 5.