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[1] [2] Other side effects of progestogens may include an increased risk of breast cancer, cardiovascular disease, and blood clots. [2] At high doses, progestogens can cause low sex hormone levels and associated side effects like sexual dysfunction and an increased risk of bone fractures. [3]
However, a number of side effects are possible, for instance mood changes. [28] If progesterone is taken by mouth or at high doses, certain central side effects including sedation, sleepiness, and cognitive impairment can also occur. [28] [20] The medication is a naturally occurring progestogen and hence is an agonist of the progesterone ...
Side effects of dienogest include menstrual irregularities, headaches, nausea, breast tenderness, depression, and acne, among others. [14] Dienogest is a progestin, or a synthetic progestogen , and hence is an agonist of the progesterone receptor , the biological target of progestogens like progesterone .
Pregnancy occurs in about 0.3% of women with perfect use and 9% of women with typical use. [3] Common side effects include irregular vaginal bleeding, nausea, sore breasts, vaginitis, mood changes, and headache. [4] Rare but serious side effects may include blood clots, toxic shock syndrome, anaphylaxis, gallstones, and liver problems. [4]
Hydroxyprogesterone caproate is generally well tolerated and produces few side effects. [1] Injection site reactions such as pain and swelling are the most common side effect of hydroxyprogesterone caproate. [1] The medication may increase the risk of gestational diabetes when used in pregnant women.
Progestogens, also sometimes written progestins, progestagens or gestagens, [1] are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). [ 2 ] [ 3 ] Progesterone is the major and most important progestogen in the body.
It may also cause glucocorticoid side effects such as Cushing syndrome-like symptoms, steroid diabetes, and adrenal insufficiency at high dosages. [ 71 ] [ 72 ] [ 73 ] Case reports of deep vein thrombosis , pulmonary embolism , jaundice , intrahepatic cholestasis , and meningiomas in association with high-dosage megestrol acetate have been ...
"Progestogen-only pills," "Progestin-only pills," and "Progesterone-only pills" are terms each referring to the same class of synthetic hormone medications.The phrase "Progestogen-only pill" is used by the World Health Organization and much of the international medical community. [7]