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This is a list of investigational autism and pervasive developmental disorder drugs, or drugs that are currently under development for clinical use in the treatment of autistic spectrum disorders and/or other pervasive developmental disorders but are not yet approved.
Proponents of orthomolecular medicine counter that some vitamins and nutrients are now used in medicine as treatments for specific diseases, such as megadose niacin and fish oil for dyslipidemias, and megavitamin therapies for a group of rare inborn errors of metabolism. [21]
Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...
Animal-assisted therapy, where an animal such as a dog or a horse becomes a basic part of a person's treatment, was a controversial treatment for some symptoms. A 2007 meta-analysis found that animal-assisted therapy was associated with "a moderate improvement in autism spectrum symptoms". [92]
Shana Nichols, the author of Girls Growing Up on the Autism Spectrum, said that it is an "excellent read" as well as a "celebration of the culture of AS womanhood." [9] Nichols also said that Simone writes with "passion, honesty and truth". [9] The book won a gold medal for the Sexuality/Relationships category in the 2011 IPPY Awards.
Which autism spectrum diagnoses can be made and which criteria are used depends on the local healthcare system's regulations. According to the DSM-5-TR (2022), in order to receive a diagnosis of autism spectrum disorder, one must present with "persistent deficits in social communication and social interaction" and "restricted, repetitive ...
Ornithine transcarbamylase deficiency also known as OTC deficiency is the most common urea cycle disorder in humans. Ornithine transcarbamylase, the defective enzyme in this disorder, is the final enzyme in the proximal portion of the urea cycle, responsible for converting carbamoyl phosphate and ornithine into citrulline.
Most parents report that the onset of autism features appear within the first or second year of life. [11] [12] This course of development is fairly gradual, in that parents typically report concerns in development over the first two years of life and diagnosis can be made around 3–4 years of age. [9]