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Gastric ulcer with a red spot seen in gastroscopy of a patient with upper gastrointestinal hemorrhage Successful closure of the gastric ulcer with an endoclip. The endoclip was first described by Hayashi and Kudoh in 1975, [1] and was termed the "staunch clip".
“A peptic ulcer is a sore or a break in the tissue that lines your stomach or small intestine,” explains Dr. Leah DeCoste, MD, a gastroenterologist with Gastro Health in Acton, Massachusetts ...
For decades prior to their discovery, it was widely believed that PUD was caused by excess acid in the stomach. During this time, acid control was the primary method of treatment for PUD, to only partial success. Among other effects, it is now known that acid suppression alters the stomach milieu to make it less amenable to H. pylori infection.
Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
The location of colonization of H. pylori, which affects the location of the ulcer, depends on the acidity of the stomach. [49] In people producing large amounts of acid, H. pylori colonizes near the pyloric antrum (exit to the duodenum) to avoid the acid-secreting parietal cells at the fundus (near the entrance to the stomach). [ 32 ]
Recording of the Electrogastrogram can be made from either the gastrointestinal surface mucosa, serosa, or the external skin surface.The cutaneous electrogastrography provides an indirect representation of the electrical activity, that has been demonstrated in numerous studies to exactly correspond to simultaneous recordings of the mucosa or serosa.
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