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Wolfram syndrome, also called DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness), is a rare autosomal-recessive genetic disorder that causes childhood-onset diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders including neurodegeneration.
Diabetes insipidus (DI) is a condition characterized by large amounts of dilute urine and increased thirst. [1] The amount of urine produced can be nearly 20 liters per day. [ 1 ] Reduction of fluid has little effect on the concentration of the urine. [ 1 ]
Untreated central diabetes insipidus patients usually exhibit polyuria, nocturia, and polydipsia as a result of the initial rise of serum sodium and osmolality. [5] Patients may also experience neurologic symptoms associated with the underlying illness, such as headaches and diplopia, depending on the exact origin of the central diabetes insipidus.
The heavily mutated COVID-19 variant is now the fastest-growing strain in the US. Experts discuss JN.1 symptoms, transmission, vaccines and more. JN.1 accounts for over 90% of US COVID cases: Know ...
However, the COVID-19 of 2023 isn't the same as the COVID-19 of 2019 and 2020—the variant that uprooted our lives. Doctors share that the disease has evolved and so has population immunity.
As respiratory virus season approaches in the U.S., some are concerned about whether XEC could cause a fall surge, and if the new COVID-19 vaccines being rolled out will protect against it.
Both cause excessive urination (hence the similarity in name), but whereas diabetes insipidus is a problem with the production of antidiuretic hormone (neurogenic diabetes insipidus) or the kidneys' response to antidiuretic hormone (nephrogenic diabetes insipidus), diabetes mellitus causes polyuria via osmotic diuresis, due to the high blood ...
The side effects of newly discovered COVID-19 strain XEC might not be as severe, but is part of the more contagious variant class, experts say.. The Centers for Disease Control and Prevention (CDC ...