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An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...
Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...
In the Netherlands, morphine is classified as a List 1 drug under the Opium Law. In New Zealand, morphine is classified as a Class B drug under the Misuse of Drugs Act 1975. [153] In the United Kingdom, morphine is listed as a Class A drug under the Misuse of Drugs Act 1971 and a Schedule 2 Controlled Drug under the Misuse of Drugs Regulations ...
epocrates is a widely used mobile medical reference application that provides healthcare professionals with access to clinical information at the point of care. The software is designed to assist physicians, pharmacists, nurse practitioners, physician assistants and other healthcare providers in making informed decisions about drug interactions, medical calculations, diagnosis and treatment ...
After injection the used tube was often pinned to the receiving soldier's collar to inform others of the dose administered. [1] The syrette was adopted for use by the United States Army in 1940. [1] The US military also distributed atropine in syrettes. [citation needed] Chemical treatment was subsequently distributed in autoinjector form ...
Dose for dose it is roughly ten times more potent than morphine, with 1 mg desomorphine being equivalent 10 mg morphine, via the intravenous (IV) or intramuscular (IM) routes. [ 10 ] Desomorphine is a morphine analogue where the 6-hydroxyl group and the 7,8 double bond have been reduced. [ 8 ]
Brompton cocktail, sometimes called Brompton mixture or Brompton's cocktail, was an elixir meant for use as a pain suppressant dosed for prophylaxis.Made from morphine or diacetylmorphine (heroin), cocaine, highly pure ethyl alcohol (some recipes specify gin), and sometimes with chlorpromazine (Thorazine) to counteract nausea, it was given to terminally ill individuals (especially cancer ...
Rapidly decreasing the dose may result in opioid withdrawal. [7] Generally, use during pregnancy or breastfeeding is not recommended. [11] Hydromorphone is believed to work by activating opioid receptors, mainly in the brain and spinal cord. [7] Hydromorphone 2 mg IV is equivalent to approximately 10 mg morphine IV. [9] Hydromorphone was ...