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22227 Ensembl ENSG00000109424 ENSMUSG00000031710 UniProt P25874 P12242 RefSeq (mRNA) NM_021833 NM_009463 RefSeq (protein) NP_068605 NP_033489 Location (UCSC) Chr 4: 140.56 – 140.57 Mb Chr 8: 84.02 – 84.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) is a mitochondrial ...
He has discussed the critical influence of ambient temperature on metabolic experiments, particularly regarding nonshivering thermogenesis and its implications for understanding mammalian metabolism, highlighting the importance of examining animals at thermoneutral temperatures. [23]
Thermogenesis is the process of heat production in organisms. It occurs in all warm-blooded animals, and also in a few species of thermogenic plants such as the Eastern skunk cabbage , the Voodoo lily ( Sauromatum venosum ), and the giant water lilies of the genus Victoria .
The human body has two methods of thermogenesis, which produces heat to raise the core body temperature. The first is shivering, which occurs in an unclothed person when the ambient air temperature is under 25 °C (77 °F) [dubious – discuss]. [18]
Additionally, almost all eutherian mammals (with the only known exception of swine) have brown adipose tissue whose mitochondria are capable of non-shivering thermogenesis. [8] This process involves the direct dissipation of the mitochondrial gradient as heat via an uncoupling protein , thereby "uncoupling" the gradient from its usual function ...
When an organism reaches this stage the metabolic rate increases significantly and thermogenesis increases the T b (body temp.) If the T a continues to decrease far below the LCT hypothermia occurs. Alternatively, evaporative heat loss for cooling occurs when temperatures above the TNZ, the upper critical zone (UCT), are realized (Speakman and ...
‐ 2 ‐ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 comported with the protocol set out in the warrant. Because this is a key issue in
Newborn babies, infants, and young children experience a greater (net) heat loss than adults because of greater surface-area-to-volume ratio. As they cannot shiver to maintain body heat, [ citation needed ] they rely on non-shivering thermogenesis .