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Optofluidic waveguides are based on principles of traditional optical waveguides and microfluidic techniques used to maintain gradients or boundaries between flowing fluids. Yang et al. used microfluidic techniques based on laminar flow to generate fluid-based gradient-indices of refraction . [ 6 ]
Optofluidic waveguides, single molecule optical analysis. United States: Caltech: Yang Biophotonics Group [30] Optofluidic Microscopy, Imaging, OCT. United States: UC San Diego: Ultrafast and Nanoscale Optics Group (Fainman) [31] Nanoscale lasers, optofluidic switches, silicon devices. United States: University of Michigan: Sherman Fan Lab [32]
Microfluidics emerged in the beginning of the 1980s and is used in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Typically, micro means one of the following features: Small volumes (μL, nL, pL, fL) Small size; Low energy consumption; Microdomain effects
A total internal reflection fluorescence microscope (TIRFM) is a type of microscope with which a thin region of a specimen, usually less than 200 nanometers can be observed. TIRFM is an imaging modality which uses the excitation of fluorescent cells in a thin optical specimen section that is supported on a glass slide.
The resolution at that time was limited to 10 µm laterally and 26 µm longitudinally but at a sample size in the millimeter range. The orthogonal-plane fluorescence optical sectioning microscope used a simple cylindrical lens for illumination. Further development and improvement of the selective plane illumination microscope started in 2004. [5]
That year S. C. Crossmon, N. B. Dodge, and co-authors R. C. Emmons and R. N. Gates all wrote papers on the use of dispersion effects through the microscope to characterize particles. [ 18 ] [ 19 ] [ 20 ] Crossmon seems to have coined the term “Dispersion Staining” as any optical technique that used the “Christiansen Effect” to produce ...
Antonie van Leeuwenhoek (1632–1723). The field of microscopy (optical microscopy) dates back to at least the 17th-century.Earlier microscopes, single lens magnifying glasses with limited magnification, date at least as far back as the wide spread use of lenses in eyeglasses in the 13th century [2] but more advanced compound microscopes first appeared in Europe around 1620 [3] [4] The ...
A bright-field microscope has many important parts including; the condenser, the objective lens, the ocular lens, the diaphragm, and the aperture. Some other pieces of the microscope that are commonly known are the arm, the head, the illuminator, the base, the stage, the adjusters, and the brightness adjuster.