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Denosumab. Denosumab, sold under the brand names Prolia and Xgeva among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. [ 8][ 9] Denosumab is contraindicated in people with low blood calcium levels.
Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used to treat osteoporosis. [ 1] They are called bisphosphonates because they have two phosphonate ( PO (OH) 2) groups.
Zoledronic acid, also known as zoledronate and sold under the brand name Zometa among others, [ 7] by Novartis among others, is a medication used to treat a number of bone diseases. [ 3] These include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, Paget's disease of bone [ 3] and Duchenne muscular dystrophy (DMD).
The drug is one of only two treatments that help to promote bone formation, and the first to reduce bone loss at the same time. First osteoporosis drug of its kind for more than a decade approved ...
The new drug is "a very well-tolerated treatment" for most people, according to Dr Nicky Peel, a clinical trustee at the Royal Osteoporosis Society and metabolic bone physician based in Sheffield.
Romosozumab, sold under the brand name Evenity, is a medication used to treat osteoporosis. [ 7][ 8] It has been found to decrease the risk of fractures of the spine. [ 7] Common side effects include headache, joint pain, and injection site reactions including pain. [ 7] It may increase the risk of heart attacks, strokes, and deaths from ...
Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [ 3] It is taken by mouth. [ 3] Use is often recommended together with vitamin D, calcium supplementation, and lifestyle changes. [ 3]
Medications related to cancer therapy, and osteoporosis in combination with dental surgery: Risk factors: Duration of anti-resorptive or anti-angiogenic drugs, intravenous vs by-mouth: Diagnostic method: Exposed bone >8 weeks: Differential diagnosis: Osteomyelitis, Osteoradionecrosis: Prevention: No definitive. Drug holiday for some patients ...
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