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Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used to treat osteoporosis. [ 1] They are called bisphosphonates because they have two phosphonate ( PO (OH) 2) groups.
15% (50 year olds), 70% (over 80 year olds) [ 7] Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly. [ 3]
Denosumab. Denosumab, sold under the brand names Prolia and Xgeva among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. [ 8][ 9] Denosumab is contraindicated in people with low blood calcium levels.
The new drug is "a very well-tolerated treatment" for most people, according to Dr Nicky Peel, a clinical trustee at the Royal Osteoporosis Society and metabolic bone physician based in Sheffield.
Osteoporosis is caused by bone loss. Most often, the reason for bone loss is very low levels of the hormone estrogen. Estrogen plays an important role in building and maintaining your bones. The ...
Romosozumab, sold under the brand name Evenity, is a medication used to treat osteoporosis. [ 7][ 8] It has been found to decrease the risk of fractures of the spine. [ 7] Common side effects include headache, joint pain, and injection site reactions including pain. [ 7] It may increase the risk of heart attacks, strokes, and deaths from ...
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