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  2. Duchenne muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Duchenne_muscular_dystrophy

    Duchenne muscular dystrophy is a rare progressive disease that eventually affects all voluntary muscles and involves the heart and breathing muscles in later stages. Life expectancy is estimated to be around 25–26, [18] [59] but this varies. People born with Duchenne muscular dystrophy after 1990 have a median life expectancy of approximately ...

  3. Muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Muscular_Dystrophy

    A less severe variant of Duchenne muscular dystrophy, [13] affects predominantly boys. Congenital muscular dystrophy: Multiple Multiple AD, AR: At birth Generalised weakness Symptoms include general muscle weakness and possible joint deformities. Disease progresses slowly, and lifespan is shortened.

  4. Pfizer reports patient death in Duchenne gene therapy study - AOL

    www.aol.com/news/pfizer-reports-patient-death...

    (Reuters) -A young patient died due to cardiac arrest after receiving Pfizer's experimental gene therapy being tested in a mid-stage trial for a muscle-wasting disorder called Duchenne muscular ...

  5. Progressive muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Progressive_muscular_atrophy

    Progressive muscular atrophy (PMA), also called Duchenne–Aran disease and Duchenne–Aran muscular atrophy, is a disorder characterised by the degeneration of lower motor neurons, resulting in generalised, progressive loss of muscle function.

  6. Dystrophinopathy - Wikipedia

    en.wikipedia.org/wiki/Dystrophinopathy

    Dystrophinopathy refers to a spectrum of diseases due to mutations in the DMD gene, which encodes for the dystrophin protein found in muscle. [1] [2] [3] The severe end of the spectrum includes Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), and DMD-associated dilated cardiomyopathy.

  7. Coxsackievirus-induced cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Coxsackievirus-induced...

    Dilated cardiomyopathy in humans can be caused by multiple factors including hereditary defects in the cytoskeletal protein dystrophin in Duchenne muscular dystrophy (DMD) patients). A heart that undergoes dilated cardiomyopathy shows unique enlargement of ventricles, and thinning of the ventricular wall that may lead to heart failure.

  8. Myotonic dystrophy - Wikipedia

    en.wikipedia.org/wiki/Myotonic_dystrophy

    Myotonic dystrophy (DM) is a genetic condition that is inherited in an autosomal dominant pattern, meaning each child of an affected individual has a 50% chance of inheriting the disease. The mutation involves satellite DNA , which is tandemly repeated sequences of DNA that do not code for a protein.

  9. I have a painful condition known as the 'suicide disease ...

    www.aol.com/news/painful-condition-known-suicide...

    Jackie Galgey, 45, shares in a personal essay her experience with trigeminal neuralgia, also called the suicide disease, which caused her one-sided facial pain.

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